RNAgri technology allows RNA to be manufactured using well proven large scale fermentation processes. Prior to RNAgri manufacturing innovations, these large scale fermentation processes were not viable because the RNA produced was almost immediately destroyed by microbial nucleases. The resulting low RNA yields resulted in RNA costs that were prohibitive for uses in agriculture.
RNAgri technology uses a protein to bind the RNA as it is produced, thus protecting it from RNAse degradation. This protein protects the RNA allowing subsequent isolation and purification. There is also a high level of interest in using the protein bound RNA as a delivery mechanism.
The adjacent video provides a basic overview of how RNA interference (RNAi) works.